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The typical form of seizures occurs within the first month of life, while in atypical patients, seizures may be delayed until infancy to 3 years of age

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The development of an oral small molecule GLP-1 receptor agonist is a significant advancement in the field of diabetes and metabolic disorders

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Integrated with the functional, pharmacological and computational data, these studies demonstrate distinct locations and different conformations of the orthosteric binding pocket between small molecule and peptidic ligands